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an that of the other adjuvants (Figure 3D). IgG subclass analysis indicated that all candidates tested significantly increased both specific IgG1 and, with the exception of chitosan, IgG2a antibody titres (p,0.01) (data not shown). gp140 when administered alone gave an IgG1/IgG2a ratio of 3.5. FSL-1, MPLA, Pam3CSK4 and chitosan increased IgG1/IgG2a ratios promoting a Th2 biasing of responses that

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